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Wednesday, November 19, 2025 , BSE Sensex : 85,206.61 85,206.61(0.63%) , Adani Ports : 1,483.25 1,483.25(-0.79%) , Asian Paints : 2,898.25 2,898.25(-0.25%) , Axis Bank : 1,270.65 1,270.65(0.43%) , Bajaj Finance : 1,005.80 1,005.80(-0.76%) , Bajaj Finserv : 2,050.35 2,050.35(0.00%) , Bharat Electron : 422.45 422.45(0.38%) , Bharti Airtel : 2,156.10 2,156.10(0.29%) , Eternal Ltd : 306.50 306.50(0.20%) , HCL Technologies : 1,666.00 1,666.00(4.47%) , HDFC Bank : 996.20 996.20(0.46%) , Hind. Unilever : 2,443.00 2,443.00(1.64%) , ICICI Bank : 1,382.10 1,382.10(0.74%) , Infosys : 1,540.05 1,540.05(3.66%) , ITC : 403.55 403.55(-0.54%) , Kotak Mah. Bank : 2,106.45 2,106.45(0.70%) , Larsen & Toubro : 4,023.20 4,023.20(0.61%) , M & M : 3,729.10 3,729.10(0.89%) , Maruti Suzuki : 15,765.00 15,765.00(-1.03%) , NTPC : 325.90 325.90(-0.81%) , Power Grid Corpn : 275.15 275.15(0.35%) , Reliance Industr : 1,519.50 1,519.50(-0.01%) , SBI : 983.30 983.30(1.11%) , Sun Pharma.Inds. : 1,783.30 1,783.30(1.34%) , Tata Motors PVeh : 361.50 361.50(-2.63%) , Tata Steel : 173.10 173.10(0.41%) , TCS : 3,149.95 3,149.95(2.08%) , Tech Mahindra : 1,441.20 1,441.20(1.41%) , Titan Company : 3,926.70 3,926.70(1.12%) , Trent : 4,363.55 4,363.55(-0.19%) , UltraTech Cem. : 11,664.30 11,664.30(-0.36%) ,

Nifty 50 : 26,061.50 151.45(0.58%) , Adani Enterp. : 2,441.50 4.70(0.19%) , Adani Ports : 1,484.20 -10.80(-0.72%) , Apollo Hospitals : 7,475.00 89.50(1.21%) , Asian Paints : 2,897.30 -8.70(-0.30%) , Axis Bank : 1,269.20 3.80(0.30%) , Bajaj Auto : 8,894.50 -26.50(-0.30%) , Bajaj Finance : 1,006.50 -7.10(-0.70%) , Bajaj Finserv : 2,050.60 0.40(0.02%) , Bharat Electron : 422.10 1.20(0.29%) , Bharti Airtel : 2,156.60 7.40(0.34%) , Cipla : 1,529.40 14.90(0.98%) , Coal India : 380.00 -3.95(-1.03%) , Dr Reddy's Labs : 1,251.80 8.00(0.64%) , Eicher Motors : 6,879.00 64.50(0.95%) , Eternal Ltd : 306.70 0.55(0.18%) , Grasim Inds : 2,749.80 -12.20(-0.44%) , HCL Technologies : 1,666.90 71.70(4.49%) , HDFC Bank : 994.15 1.70(0.17%) , HDFC Life Insur. : 761.25 -0.55(-0.07%) , Hind. Unilever : 2,444.80 40.80(1.70%) , Hindalco Inds. : 792.70 -4.45(-0.56%) , ICICI Bank : 1,381.70 8.30(0.60%) , Infosys : 1,541.80 55.40(3.73%) , Interglobe Aviat : 5,746.00 6.50(0.11%) , ITC : 403.80 -2.05(-0.51%) , Jio Financial : 305.35 -0.60(-0.20%) , JSW Steel : 1,166.50 3.50(0.30%) , Kotak Mah. Bank : 2,106.30 13.20(0.63%) , Larsen & Toubro : 4,022.80 23.20(0.58%) , M & M : 3,730.00 35.20(0.95%) , Maruti Suzuki : 15,757.00 -173.00(-1.09%) , Max Healthcare : 1,168.50 51.80(4.64%) , Nestle India : 1,277.20 12.10(0.96%) , NTPC : 326.40 -2.05(-0.62%) , O N G C : 249.80 2.85(1.15%) , Power Grid Corpn : 275.05 0.85(0.31%) , Reliance Industr : 1,520.90 1.50(0.10%) , SBI : 983.10 10.65(1.10%) , SBI Life Insuran : 2,004.40 11.10(0.56%) , Shriram Finance : 819.10 -1.10(-0.13%) , Sun Pharma.Inds. : 1,789.00 30.20(1.72%) , Tata Consumer : 1,164.20 10.10(0.88%) , Tata Motors PVeh : 361.40 -9.90(-2.67%) , Tata Steel : 173.52 1.07(0.62%) , TCS : 3,152.10 65.00(2.11%) , Tech Mahindra : 1,441.70 19.70(1.39%) , Titan Company : 3,915.00 35.80(0.92%) , Trent : 4,360.90 -13.10(-0.30%) , UltraTech Cem. : 11,678.00 -29.00(-0.25%) , Wipro : 246.25 5.35(2.22%) , Wednesday, November 19, 2025

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17-Nov-2025     13:00
Shilpa Medicare launches NODUCA™ therapy in India
Shilpa Medicare announced the launch of NODUCA™ (Nor Ursodeoxycholic Acid (NorUDCA)), a first-in-class therapy for the first time in India or anywhere in the world, following the historic approval granted in August 2025 by the Central Drugs Standard Control Organisation (CDSCO), India. The drugs ushers in a new line of treatment for patients suffering from metabolic dysfunction-associated fatty liver disease (MAFLD), previously referred to as non-alcoholic fatty liver disease (NAFLD).

NorUDCA offers three major therapeutic benefits for MAFLD and associated liver disorders:

- Anti-inflammatory action: Actively reduces hepatic and ductular inflammation, limiting progression to cirrhosis and liver failure.

- Anti-fibrotic effect: Promotes reversal of liver scarring (fibrosis) and stabilizes liver architecture, as proven in Phase 3 studies, with 83.3% of patients showing fibrosis reversal and 90% achieving normal liver enzyme levels within 3 months.

- Choleretic protection: Encourages toxin clearance via enhanced bile secretion and protects cholangiocytes, minimizing risk of advanced disease.

NODUCA™ (norursodeoxycholic acid), a novel bile acid therapy designed to treat metabolic dysfunction associated fatty liver disease (MAFLD), offers a first-in-class approach to improving liver health by reducing inflammation, fibrosis, and cholestasis through unique mechanisms distinct from conventional therapies.

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